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CASIN was used at 5 µM final concentration in the in vitro assays and ex vivo treatment of HSCs
5-trimethoxyphenyl)amino)pyrimidin-4-yl)oxy)-N-methylbenzamide
It abrogated DNA damaged checkpoints induced by gemcitabine
CAS Number: 68047-06-3
iPSC-TSPC 0244 CASIN was used at 5Product Information Purity: 98% for each compound Storage: 4oC for 3 month. 20oC for 6 month. Cocktail Formulation: 5 mM Thiazovivin, 2 mM SB 431542, 0. 4 mM PD0325901 and 1 mM CHIR99021 in DMSO. Biological Activity: Extensive studies have shown that individual Rock inhibitor (Thiazovivin), TGF inhibitor (SB431542), MEK inhibitor (PD0325901), GSK3 inhibitor (CHIR99021), , and their combinations (TSPC) can significantly enhance reprogramming efficiency