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the human breast cancer MDA-MB-453 cells and the normal mouse fibroblasts (NIH 3T3)
a patient-derived tamoxifen-resistant xenograft tumor
2010 Sep 15
Staurosporine is a prototypical ATP-competitive kinase inhibitor in that it binds to many kinases with high affinity
MS 154N Size:2mg solid the human breast cancer MDA-MB-453MS 154N is a negative control for MS 154. The compound exhibits high binding affinity for WT and L858R mutant EGFR (Kd values are 3 and 4. 3 nM, respectively), but does not significantly induce degradation of EGFR mutants. Product information Molecular Weight: 915. 45 Formula: C47H56ClFN8O8 Chemical Name: 3 (4 (3 ((4 ((3 chloro 4 fluorophenyl)amino) 7 methoxyquinazolin 6 yl)oxy)propyl)piperazin 1 yl) N (8 ((2 (1 methyl 2,6 dioxopiperidin 3 yl) 1,3