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Formula: C28H33N7O2
26-tetraazapentacyclo[24
Formula: C13H11N2NaO2
a downstream target of the Wnt/β-catenin pathway
MLN4924 Hydrochloride - CAS# 1160295-21-5 Catalog No.:M10954-2 Formula: C28H33N7O2Pevonedistat, also known as MLN 4924 and TAK 924, is a small molecule inhibitor of Nedd8 activating enzyme (NAE) with potential antineoplastic activity. NAE inhibitor MLN4924 binds to and inhibits NAE, which may result in the inhibition of tumor cell proliferation and survival. NAE activates Nedd8 (Neural precursor cell expressed, developmentally down regulated 8), an ubiquitin like (UBL) protein that modifies cellular targets in a pathway that is
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