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GSK0660 antagonizes 100% of the activity of PPARβ/δ with a pIC50 of 6
Formula: C22H24ClN3O4
76(11):3340-50
and 200 mg/kg results in mean tumor regression of 92%
Retigabine dihydrochloride Catalog No.:M9949-10 GSK0660 antagonizes 100% of theEzogabine, also known as Retigabine, is an anticonvulsant used as an adjunctive treatment for partial epilepsies in treatment experienced adult patients. The drug was developed by Valeant Pharmaceuticals and GlaxoSmithKline. Ezogabine works primarily as a potassium channel openerthat is, by activating a certain family of voltage gated potassium channels in the brain. This mechanism of action is unique among antiepileptic drugs, and may hold promise
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