I-BET282E - CAS# 2885162-99-0 Catalog No.:M34971-C 4-7H3/b21-18-/t22-

4-7H3/b21-18-/t22-

CAS Number: 480-16-0

521 reduces constitutive expression of interferon in macrophages from a mouse model of Aicardi-Goutières syndrome (AGS)

and TYR89) are key to the activation site of LYN-1604 and ULK1 by site-directed mutagenesis and biochemical assays

I-BET282E - CAS# 2885162-99-0 Catalog No.:M34971-C 4-7H3/b21-18-/t22-I BET282E is a pan inhibitor of all eight BET bromodomains, and selectivity over other representative bromodomain containing proteins. I BET282E shows pIC50s ranging 6. 4 7. 7 for BRD2 (BD1 BD2), BRD2 (BD1 BD), BRD3 (BD1 BD), and BRD4 (BD1 BD). Product information CAS Number: 2885162 99 0 Molecular Weight: 546. 64 Formula: C26H34N4O7S Chemical Name: 4 {8 methoxy 1 [(2R) 1 methoxypropan 2 yl] 2 (oxan 4 yl) 1H imidazo[4,5 c]quinolin 7 yl} 3,5 dimethyl