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Saracatinib - CAS# 379231-04-6 Catalog No.:M7189-2 2010 Oct 30 [updated 2013

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Description

2010 Oct 30 [updated 2013 Feb 28]

21(8):883-891

bolus doses of 25 mg/kg

As a tool compound

Saracatinib - CAS# 379231-04-6 Catalog No.:M7189-2 2010 Oct 30 [updated 2013Saracatinib, CAS No. 379231 04 6, also known as AZD0530, is an orally available dual specific inhibitor of Src and Abl with anti invasive and anti tumor activities. Src and Abl are protein tyrosine kinases that are overexpressed in chronic myeloid leukemia cells. Saracatinib binds to and inhibits these tyrosine kinases and their effects on cell motility, cell migration, adhesion, invasion, proliferation, differentiation, and survival. Product

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