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1 µM AZD5904 inhibits PMA stimulated HOCl by >90%
TD-165 is a PROTAC-based cereblon (CRBN) degrader
InChi: InChI=1S/C21H24FN5O5S/c1-13(2)31-21(28)26-8-6-14(7-9-26)32-20-16-11-25-27(19(16)23-12-24-20)18-5-4-15(10-17(18)22)33(3
cleave a specific extracellular amino-terminal domain of the receptor to reveal a "tethered ligand"
SRI-29329 848ihydrolycorine 1 µM AZD5904 inhibits PMASRI 29329 is a specific CLK inhibitor, with IC50 values of 78 nM, 16 nM and 86 nM for CLK1, CLK2 and CLK4, respectively. Product information CAS Number: 2086809 58 5 Molecular Weight: 399. 92 Formula: C20H26ClN7 Chemical Name: N2 [(1S,2S) 2 aminocyclohexyl] N6 (3 chlorophenyl) 9 (propan 2 yl) 9H purine 2,6 diamine Smiles: CC(C)N1C=NC2=C(NC3=CC=CC(Cl)=C3)N=C(N[C@H]3CCCC[C@@H]3N)N=C12 InChiKey: JPJBCKSRGYPABG HOTGVXAUSA N InChi: InChI=1S C20H26ClN7 c1