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Naratriptan icorandil 4-dichlorophenyl)methyl]amino]-adenosine

SKU: 11220411833

4.9
USD85.00 USD110.00

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Description

4-dichlorophenyl)methyl]amino]-adenosine

Smiles: N[C@@H](CC1C=CC=CC=1)C(=O)N1C/C(=C\C2=CC(Cl)=C(Cl)C=C2)/C(=O)/C(/C1)=C/C1=CC(Cl)=C(Cl)C=C1

Molecular Weight: 255

InChi: InChI=1S/C25H33N7O2/c1-2-3-12-27-25-29-16-22(23(31-25)30-19-6-10-21(33)11-7-19)24(34)28-15-18-4-8-20(9-5-18)32-14-13-26-17-32/h4-5

Naratriptan icorandil 4-dichlorophenyl)methyl]amino]-adenosineNaratriptan is a selective 5 HT1 receptor subtype agonist for the treatment of migraine headache. Naratriptan binds with high affinity to human cloned 5 HT1B 1D receptors. Migraines are likely due to local cranial vasodilatation and or to the release of sensory neuropeptides (including substance P and calcitonin gene related peptide) through nerve endings in the trigeminal system. The therapeutic activity of AMERGE for the treatment of migraine

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