ZM223 - CAS# 2031177-48-5 Catalog No.:M16010-C Smiles: CCOC(=O)C1=C(NC(=O)CN2CCN(CC2)C(=O)C2=CC=CO2)SC2CCCC1=2

Smiles: CCOC(=O)C1=C(NC(=O)CN2CCN(CC2)C(=O)C2=CC=CO2)SC2CCCC1=2

Xanthohumol significantly reduces cell viability and induces apoptosis via pro-caspase-3/8 cleavage and poly(ADP ribose) polymerase (PARP) degradation

that exhibits antimicrobial activity against S

K562 cells) treatment increases cell population in the sub-G1 phase in K562 cells

ZM223 - CAS# 2031177-48-5 Catalog No.:M16010-C Smiles: CCOC(=O)C1=C(NC(=O)CN2CCN(CC2)C(=O)C2=CC=CO2)SC2CCCC1=2ZM223 is a potent non covalent NEDD8 activating enzyme (NAE) inhibitor, orally active. Product information CAS Number: 2031177 48 5 Molecular Weight: 502. 53 Formula: C23H17F3N4O2S2 Chemical Name: N [6 [[2 (4 aminophenyl)sulfanylacetyl]amino] 1, 3 benzothiazol 2 yl] 4 (trifluoromethyl)benzamide Smiles: NC1C=CC(=CC=1)SCC(=O)NC1=CC=C2N=C(NC(=O)C3C=CC(=CC=3)C(F)(F)F)SC2=C1 InChiKey: XPPKZMFJCSEUSX UHFFFAOYSA N InChi: InChI=1S C23H17F3N4O2S2 c24