Licofelone-d4 one D6 hydrochloride Smiles: [2H]C([2H])([2H])C(=O)N[C@H]1CCC2=CC(OC)=C(OC)C(OC)=C2C2C=CC(=O)C(=CC=21)OC

Smiles: [2H]C([2H])([2H])C(=O)N[C@H]1CCC2=CC(OC)=C(OC)C(OC)=C2C2C=CC(=O)C(=CC=21)OC

Smiles: COC1=C(C=C2OC=C(C(=O)C2=C1O)C1=CC(O)=C(OC)C(=C1)OC)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

Molecular Weight: 1729

N-Boc-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs

Licofelone-d4 one D6 hydrochloride Smiles: [2H]C([2H])([2H])C(=O)N[C@H]1CCC2=CC(OC)=C(OC)C(OC)=C2C2C=CC(=O)C(=CC=21)OCLicofelone d4 (ML 3000 d4) is the deuterium labeled Licofelone. Licofelone (ML 3000) is a dual COX 5 lipoxygenase (5 LOX) inhibitor (IC50=0. 21 0. 18 M, respectively) for the treatment of osteoarthritis. Licofelone exerts anti inflammatory and anti proliferative effects. Licofelone induces apoptosis, and decreases the production of proinflammatory leukotrienes and prostaglandins. Product information CAS Number: 1189427 04 0 Molecular Weight: 383. 90