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TAK-715 odiamide hydrate Acetazolamide D3 is deuterium labeled

SKU: 13299023078

4.1
USD90.00 USD114.00

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Description

Acetazolamide D3 is deuterium labeled Acetazolamide

InChiKey: ZRZNJUXESFHSIO-FEOSZSLTSA-N

InChiKey: PKCHFYZACODWAI-STZFKDTASA-N

CAS Number: 83280-65-3

TAK-715 odiamide hydrate Acetazolamide D3 is deuterium labeledTAK 715 is a potent p38 MAPK inhibitor. which displays potent inhibitory activity (inhibition of p38alpha, IC50 = 7. 1 nM; LPS stimulated release of TNF alpha from THP 1, IC50 = 48 nM; LPS induced TNF alpha production in mice, 87. 6% inhibition at 10 mg kg, po) and no inhibitory activity for major CYPs, including CYP3A4. TAK 715 was selected as a clinical candidate and is now under clinical investigation for the treatment of RA. Product information

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