Bomedemstat ditosylate Catalog No.:M33503-C InChi: InChI=1S/C15H20O3/c1-8-4-5-11-9(2)14(16)18-13(11)12-10(8)6-7-15(12

InChi: InChI=1S/C15H20O3/c1-8-4-5-11-9(2)14(16)18-13(11)12-10(8)6-7-15(12

Acute (5 g/kg) and chronic (25 and 250 mg/kg) toxicology studies in uninfected mice show that

CAS Number: 63912-16-3

and in most cases over 99% of the very large inocula are killed within 2 h

Bomedemstat ditosylate Catalog No.:M33503-C InChi: InChI=1S/C15H20O3/c1-8-4-5-11-9(2)14(16)18-13(11)12-10(8)6-7-15(12Bomedemstat, also known as IMG 7289, is a lysine specific histone demethylase 1 (LSD1) inhibitor with antineoplastic activity. Bomedemstat may be useful in the treatment of acute myeloid leukaemia, myelodysplastic syndrome, and Myelofibrosis. IMG 7289 selectively inhibited proliferation and induced apoptosis of JAK2 V617F cells by concomitantly increasing expression and methylation of p53, and, independently, the pro apoptotic factor PUMA and by