Marein Catalog No.:M13748-10 2010 Oct 30 [updated 2013

2010 Oct 30 [updated 2013 Feb 28]

Abamectin B1b

Mogrol (0-250 µM) significantly and dose- and time-dependently inhibits K562 cell growth and increases the number of apoptotic cells

Smiles: CS(=O)(=O)OCCCCOS(C)(=O)=O

Marein Catalog No.:M13748-10 2010 Oct 30 [updated 2013Marein has the neuroprotective effect due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway. Marein improves insulin resistance induced by high glucose in HepG2 cells through CaMKK AMPK GLUT1 to promote glucose uptake, through IRS Akt GSK 3 to increase glycogen synthesis, and through Akt FoxO1 to decrease gluconeogenesis. Marein is a HDAC inhibitor with an IC50 of 100 M. Marein has beneficial antioxidative,