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tumor necrosis factor-α
TPPB inhibits the activation of caspase-3 induced by Aβ25-35
07 µM and ~0
Small-molecule activation of neuronal cell fate
CL-387785 - CAS# 194423-06-8 Catalog No.:M7079-10 tumor necrosis factor-αCL 387785, CAS No. 194423 06 8, also known as EKI 785 , is a n irreversible inhibitor of EGF receptor (EGFR) kinase activity in vivo (IC50 = 250 490 pM). CL 387785 covalently bound to EGF R. It also specifically inhibited kinase activity of the protein (IC50 = 370+ 120 pM), blocked EGF stimulated autophosphorylation of the receptor in cells (ic50 approximately 5 nM), inhibited cell proliferation (IC50 = 31 125 nM) primarily in a cytostatic manner in
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