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GSK3α/GSK3β at Ser21/Ser9 and Foxo-1/3a at Thr24/Thr32
Ciacciarelli M
8-fold increase in GPR120 mRNA expression
Azimilide has shown excellent efficacy (>85%) in suppressing supraventricular arrhythmias in a variety of dog models
INCB 3284 Catalog No.:M8437-2 GSK3α/GSK3β at Ser21/Ser9 and Foxo-1/3aINCB 3284 is a potent, selective, and orally bioavailable hCCR2 antagonist. Product information CAS Number: 887401 92 5 Molecular Weight: 520. 54 Formula: C26H31F3N4O4 Synonym: INCB 3284 Chemical Name: N [(3R) 1 [4 hydroxy 4 (6 methoxypyridin 3 yl)cyclohexyl]pyrrolidin 3 yl] 2 {[3 (trifluoromethyl)phenyl]formamido}acetamide Smiles: COC1=CC=C(C=N1)C1(O)CCC(CC1)N1C[C@@H](CC1)NC(=O)CNC(=O)C1=CC(=CC=C1)C(F)(F)F InChiKey: NXZNYBUBXWWKCP JMOWIOHXSA N InChi: