SGI-110 Size:Solid 10 mg It has Gram-negative coverage which

It has Gram-negative coverage which includes Pseudomonas aeruginosa but limited Gram-positive coverage

(2013) ACS Chem Biol

TH588 was dosed to the mice by subcutaneous administration at 30 mg/kg once per day for 21 days

2- c]pyridin-5(6H)-yl)ethanone

SGI-110 Size:Solid 10 mg It has Gram-negative coverage whichGuadecitabine, aslo known as SGI 110, is a dinucleotide antimetabolite of a decitabine linked via phosphodiester bond to a guanosine, with potential antineoplastic activity. Following metabolic activation by phosphorylation and incorporation into DNA, SGI 110 inhibits DNA methyltransferase, thereby causing genome wide and non specific hypomethylation and inducing cell cycle arrest at S phase. This agent is resistant to cytidine deaminase, hence may