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A-443654 induces rapid Akt Ser-473 phosphorylation independent of mTORC1 inhibition
InChiKey: WZXAGWREMCSWMF-YPLGJCPNSA-N
11b-octahydrodibenzo[de
and long half-lives in rat
A-77636 hydrochloride - CAS# 145307-34-2 5264 A-443654 induces rapid Akt Ser-473A 77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7. 40; Ki=39. 8 nM) with antiparkinsonian activity. A 77636 hydrochloride is functionally inactive at dopamine D2 receptor. Product information CAS Number: 145307 34 2 Molecular Weight: 365. 89 Formula: C20H28ClNO3 Chemical Name: (1R, 3S) 3 (adamantan 1 yl) 1 (aminomethyl) 3, 4 dihydro 1H 2 benzopyran 5, 6 diol hydrochloride Smiles: Cl.
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