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BSJ-03-123 exploits protein-interface determinants to achieve proteome-wide selectivity for the degradation of cyclin-dependent kinase 6 (CDK6)
3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro
Molecular Weight: 2781
Ackerman J
ACT-132577 Size:Solid 10 mg BSJ-03-123 exploits protein-interface determinants toAprocitentan, also known as ACT 132577, is an endothelin receptor antagonist and an pharmacologically active metabolite of macitentan. Aprocitentan antagonized the specific binding of ET 1 on membranes of cells overexpressing ET(A) and ET(B) receptors and blunted ET 1 induced calcium mobilization in various natural cell lines, with inhibitory constants within the nanomolar range. Product information CAS Number: 1103522 45 7 Molecular Weight: 546. 19
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