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Melphalan 195 PubMed PMID: 26586956

SKU: 24418729142

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Description

PubMed PMID: 26586956

Formula: C12H7Cl2NO3S2

Formula: C34H52N2O4

Smiles: CC1N=CSC=1C1C=CC(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCNC(=O)COC2=CC(=CC=C2)[C@@H](CCC2=CC(OC)=C(C=C2)OC)OC(=O)[C@@H]2CCCCN2C(=O)[C@@H](CC)C2C=C(OC)C(OC)=C(C=2)OC)C(C)(C)C)=CC=1

Melphalan 195 PubMed PMID: 26586956Melphalan is an orally available phenylalanine derivative of nitrogen mustard with antineoplastic activity. Melphalan alkylates DNA at the N7 position of guanine and induces DNA inter strand cross linkages, resulting in the inhibition of DNA and RNA synthesis and cytotoxicity against both dividing and non dividing tumor cells. Product information CAS Number: 148 82 3 Molecular Weight: 305. 20 Formula: C13H18Cl2N2O2 Synonym: Alkeran Sarcolysin L PAM

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