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Chemical Name: (3R)-2'-[(4-bromo-2-fluorophenyl)methyl]-2'
CI-949 is an effective inhibitor of release of all three mediators in response to this stimulus
Wortmannin prevents nuclear entry of YAP[6]
EW-7197 Hydrochloride (40 mg/kg
Cl-amidine hydrochloride RP Chemical Name: (3R)-2'-[(4-bromo-2-fluorophenyl)methyl]-2'Cl amidine hydrochloride is an orally active peptidylarginine deminase (PAD) inhibitor, with IC50 values of 0. 8 M, 6. 2 M and 5. 9 M for PAD1, PAD3, and PAD4, respectively. Cl amidine hydrochloride induces apoptosis in cancer cells. Cl amidine hydrochloride induces microRNA (miR) 16 (miRNA 16, microRNA 16) expression and causes cell cycle arrest. Cl Amidine hydrochloride prevents histone 3 citrullination and neutrophil extracellular trap formation,