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23-12-2-5-15-18(8-12)26-19-9-13(24)3-6-16(19)21(15)17-7-11(22-10-28)1-4-14(17)20(25)27-21/h2*1-9
whereas only slight activation is observed in the absence of either of them or when the enzyme is heat inactivated
TUG-770 shows excellent stability toward human liver microsomes (HLM)
JSH-23 treatment significantly reversed the nerve conduction and nerve blood flow deficits seen in diabetic animals
WAY-100635 Maleate e propionate 23-12-2-5-15-18(8-12)26-19-9-13(24)3-6-16(19)21(15)17-7-11(22-10-28)1-4-14(17)20(25)27-21/h2*1-9WAY 100635 maleate is a potent and selective 5 hydroxytryptamine 1A (5 HT1A) receptor antagonist with an IC50 value of 0. 91 nM and Ki value of 0. 39 nM. WAY 100635 maleate has pIC50 values for 5 HT1A and 1 adrenergic receptors of 8. 9 and 6. 6, respectively. WAY 100635 maleate is also a potent dopamine D4 receptor agonist. Product information CAS Number: 1092679 51 0 Molecular Weight: 538. 64 Formula: C29H38N4O6 Chemical Name: (2Z) but 2 enedioic