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Syk Inhibitor II P 14 InChi: InChI=1S/C17H20O7/c1-10-11(4-5-23-7-6-21-2)17(20)24-16-12(10)8-14(22-3)15(19)13(16)9-18/h8-9

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Description

InChi: InChI=1S/C17H20O7/c1-10-11(4-5-23-7-6-21-2)17(20)24-16-12(10)8-14(22-3)15(19)13(16)9-18/h8-9

InChi: InChI=1S/C81H140N20O23/c1-16-45(12)65(98-72(114)54(38-60(85)105)92-74(116)58-26-22-34-101(58)80(122)56(37-42(6)7)95-75(117)63(43(8)9)96-61(106)39-86-48(15)103)77(119)90-51(27-29-59(84)104)68(110)87-46(13)67(109)97-64(44(10)11)76(118)93-53(35-40(2)3)71(113)94-55(36-41(4)5)79(121)100-33-21-25-57(100)73(115)89-49(23-17-19-31-82)69(111)88-50(24-18-20-32-83)70(112)99-66(47(14)102)78(120)91-52(81(123)124)28-30-62(107)108/h40-47

38)39/h9-14

InChi: InChI=1S/C71H124N22O17/c1-11-40(9)56(93-62(103)44(23-16-17-27-72)86-69(110)57(41(10)12-2)92-59(100)43(73)22-18-28-80-70(76)77)68(109)82-35-54(96)83-48(31-38(5)6)63(104)89-50(33-42-20-14-13-15-21-42)65(106)90-51(34-55(97)98)66(107)85-46(25-26-53(74)95)61(102)88-49(32-39(7)8)64(105)91-52(36-94)67(108)84-45(24-19-29-81-71(78)79)60(101)87-47(58(75)99)30-37(3)4/h13-15

Syk Inhibitor II P 14 InChi: InChI=1S/C17H20O7/c1-10-11(4-5-23-7-6-21-2)17(20)24-16-12(10)8-14(22-3)15(19)13(16)9-18/h8-9Syk Inhibitor II is a potent, high selective and ATP competitive Syk inhibitor with an IC50 of 41 nM. Syk Inhibitor II inhibits 5 HT release from RBL cells with an IC50 of 460 nM. Syk Inhibitor II shows less potent against other kinases and has anti allergic effect. Product information CAS Number: 726695 51 8 Molecular Weight: 340. 30 Formula: C14H15F3N6O Chemical Name: 2 [(2 aminoethyl)amino] 4 {[3 (trifluoromethyl)phenyl]amino}pyrimidine 5

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