JH-XI-10-02 Catalog No.:M14601-2 4-dimethylphenyl)-5-methyl-3-oxo-2

4-dimethylphenyl)-5-methyl-3-oxo-2

InChi: InChI=1S/C16H17ClN2OS

YH25448 more potently inhibits cancer cell growth and significantly increases tumor cell apoptosis compared to osimertinib

even at super immunosuppressive doses

JH-XI-10-02 Catalog No.:M14601-2 4-dimethylphenyl)-5-methyl-3-oxo-2JH XI 10 02 is a highly potent and selective PROTAC CDK8 degrader, with an IC50 of 159 nM. JH XI 10 02 causes proteasomal degradation, does not affect CDK8 mRNA levels. JH XI 10 02 shows no effect on CDK19. Product information CAS Number: 2209085 22 1 Molecular Weight: 920. 14 Formula: C53H69N5O9 Chemical Name: N [(1S,3aS,3bR,5aS,7S,9aS,9bS,11aS) 3a,3b,5a,9b tetrahydrogenio 1 (isoquinolin 7 yl) 9a,11a dimethyl hexadecahydro 1H cyclopenta[a]phenanthren