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Epub 2014 Jul 30
Chemical Name: 1-(3-Hydroxybenzyl)-3-(4-(pyridin-4-yl)thiazol-2-yl)urea
a type of aromatic compound that occurs widely in nature
with mean IC50 values ranging from 13 to 54 nM for AZD-9291
PNU-159682 60424 Epub 2014 Jul 30PNU 159682 is a major active metabolite of nemorubicin (MMDX) in human liver microsomes. PNU 159682 showed > 3,000 fold cytotoxic than its parent compound(MMDX and doxorubicin). PNU 159682 interacts with DNA fragments d(CGTACG)(2), d(CGATCG)(2) and d(CGCGCG)(2) and shows a strong but reversible binding to G: C base pairs. Product information CAS Number: 202350 68 3 Molecular Weight: 641. 62 Formula: C32H35NO13 Synonym: PNU159682 PNU 159682 Chemical
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