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CCG-222740 markedly decreased SRF reporter gene activity and showed a greater inhibitory effect on MRTF/SRF target genes than the previously described MRTF-A inhibitor CCG-203971
1951408-58-4
1-5H3/t15-
Chemical Name: 2-[4-[2-Fluoro-5-[3-(6-methylpyridine-2-yl)-1H-pyrazol-4-yl] phenyl] pyrazol-1-yl]ethanol
cis MZ 1 60116 CCG-222740 markedly decreased SRF reporterNegative Control for MZ1 (Cat. No. 6154). Exhibits no significant VHL binding affinity. Product information CAS Number: 1797406 72 4 Molecular Weight: 1002. 64 Formula: C49H60ClN9O8S2 Chemical Name: (2S, 4S) 1 ((S) 2 (tert butyl) 17 ((S) 4 (4 chlorophenyl) 2, 3, 9 trimethyl 6H thieno[3, 2 f][1, 2, 4]triazolo[4, 3 a][1, 4]diazepin 6 yl) 4, 16 dioxo 6, 9, 12 trioxa 3, 15 diazaheptadecanoyl) 4 hydroxy N (4 (4 methylthiazol 5 yl)benzyl)pyrrolidine 2