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2 and 127%
Aminooxyacetate hemihydrochloride
2-a]pyrimidin-6-yl)cyclopropane-1-carbonitrile
ClH/c26-21-11-14-23(22(27)24-21
OG-L002 HCl 2623 2 and 127%OG L002 is a specific and potent inhibitor of lysine (K) specific demethylase 1A (LSD1) with IC50 value of 20 nM . LSD1 is a flavin dependent monoamine oxidase, which can demethylate lysines. LSD1 plays critical roles in oocyte growth, embryogenesis and tissue specific differentiation . OG L002 potently inhibited HSV IE gene expression in both HFF and HeLa cells with IC50 of ~3 M and ~10 M, respectively. OG L002 treatment can potently reduce
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