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RS-127445 administered at 1 to 10 mg/kg with oral significantly inhibits visceral hypersensitivity up to 35 to 74% provoked by restraint stress
PubMed Central PMCID: PMC3493679
High WM Jr
such as leukemia and glioma
LTI-291 - CAS# 1919820-28-2 267 RS-127445 administered at 1 toLTI 291, CAS No. 1919820 28 2, is a glucocerebrosidase (Gcase) activator for treatment of Parkinson's disease (PD). Product information CAS Number: 1919820 28 2 Molecular Weight: 358. 48 Formula: C20H30N4O2 Synonym: LTI 291 LTI 291 LTI291 Chemical Name: 5,7 Dimethyl pyrazolo[1,5 a]pyrimidine 3 carboxylic acid (trans 4 pentyloxy cyclohexyl) amide Smiles: CCCCCO[C@@H]1CC[C@H](CC1)NC(=O)C1C=NN2C=1N=C(C)C=C2C InChiKey: HZILSILAELSWKN QAQDUYKDSA N InChi: