Palosuran hydrochloride imidazole Smiles: NC(=O)C1=NN(C=C1NC(=O)C1=COC(=N1)C1=CC(NCC(F)(F)F)=NC=C1)C1=CC=C(CNCCOCCOCCNC2=CC=CC3=C2C(=O)N(C2CCC(=O)NC2=O)C3=O)C=C1

Smiles: NC(=O)C1=NN(C=C1NC(=O)C1=COC(=N1)C1=CC(NCC(F)(F)F)=NC=C1)C1=CC=C(CNCCOCCOCCNC2=CC=CC3=C2C(=O)N(C2CCC(=O)NC2=O)C3=O)C=C1

Increased arylhydrocarbon receptor expression offers a potential therapeutic target for pancreatic cancer

CAS Number: 2368870-39-5

associated with decreased levels of CCL4

Palosuran hydrochloride imidazole Smiles: NC(=O)C1=NN(C=C1NC(=O)C1=COC(=N1)C1=CC(NCC(F)(F)F)=NC=C1)C1=CC=C(CNCCOCCOCCNC2=CC=CC3=C2C(=O)N(C2CCC(=O)NC2=O)C3=O)C=C1Palosuran hydrochloride (ACT 058362 hydrochloride) is a potent, selective, and orally active antagonist of urotensin II receptor, with an IC50 of 3. 6 nM for CHO cell membranes expressing human recombinant receptors. Palosuran hydrochloride can improves pancreatic and renal function in diabetic rats. Product information CAS Number: 2469274 58 4 Molecular Weight: 454. 99 Formula: C25H31ClN4O2 Chemical Name: 1 [2 (4 benzyl 4 hydroxypiperidin 1 yl)ethyl]