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Smiles: O=C(NCC1C=CC=CC=1)C1=CSC(NC2=CC=NC=N2)=N1
is a potent and selective IDH2 inhibitor with potential anticancer activity (IDH2 = Isocitrate dehydrogenase 2)
It can also improve the efficiency of reprogramming of stem cells
YC-1 effectively inhibits tumor invasion and metastasis
ROC-325 - CAS# 1859141-26-6 size:2mg solid Smiles: O=C(NCC1C=CC=CC=1)C1=CSC(NC2=CC=NC=N2)=N1ROC 325, CAS No. 1859141 26 6, is an autophagy inhibitor. ROC 325 exhibited superior in vitro anticancer effects compared with the existing autophagy inhibitor hydroxychloroquine (HCQ) in 12 different cancer cell lines with diverse genetic backgrounds. ROC 325 antagonized RCC growth and survival in an ATG5 7 dependent manner, induced apoptosis, and exhibited favorable selectivity. Product information CAS Number: 1859141 26 6 Molecular Weight: 503. 06
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