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Labrecque J
HER-2 (IC50 19 nM) and ErbB-4 (IC50 7 nM)
4R)-5-(pyridin-2-yl)-2
TGF-β RI Kinase Inhibitor V
Cetirizine dihydrochloride thine HCl H2O Labrecque JCetirizine hydrochloride is a potent second generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen induced asthma. Cetirizine hydrochloride is a carboxylated metabolite of hydroxyzine that acts as a selective Histamine H1 receptor inverse agonist. Compared to its parent compound, it shows similar antihistaminic activity, but with greater H1 selectivity and less sedative effects.
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