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BRL54443 is a potent 5-ht1E/1F receptor agonist
GNF-5 is a selective allosteric inhibitor of Bcr-Abl (IC50 = 220 nM for wild-type Abl)
Higher doses of WM-8014 (up to 40 μM) did not accelerate growth arrest
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BI-187004 - CAS# 1303515-32-3 Catalog No.:M11474-10 BRL54443 is a potent 5-ht1E/1FBI 187004, also known as VTP 34072, is an 11 hydroxysteroid dehydrogenase 1 inhibitor. BI187004 VTP 34072 is being studied for the treatment of type 2 diabetes and metabolic syndrome. In preclinical studies, BI187004 VTP 34072 had a positive impact on multiple cardiovascular and metabolic risk factors associated with metabolic syndrome, which differentiates it from other classes of type 2 diabetes drugs. Product information CAS Number: 1303515 32 3