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while having no effect on a healthy spleen in Myc-induced lymphomas mouse model
BPTES (10 µM) reduces glutaminase activity in both WT and mutant IDH1 expressing cells
Mitoxantrone free base
Chemical Name: N-(9
DK419 - CAS# 2102672-22-8 Catalog No.:M6956-10 while having no effect onDK419, CAS No. 2102672 22 8, is a potent inhibitor of Wnt catenin signaling and colorectal cancer growth. DK419 inhibited Wnt catenin signaling, altered cellular oxygen consumption rate and induced production of pAMPK. DK419 inhibited the growth of CRC tumor cells in vitro, had good plasma exposure when dosed orally, and inhibited the growth of patient derived CRC240 tumor explants in mice dosed orally. Product information CAS Number: 2102672 22 8
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