GSK3α/GSK3β at Ser21/Ser9 and Foxo-1/3a at Thr24/Thr32
H3K27 methylations play important roles in regulating gene expression through the polycomb-repressive complex (PRC1 or PRC2)
Co-treatment with both 50 μM BRL 49653 and 10 μM GW-9662 results in statistically lower viable cell numbers after 7 days when compared to treatment with either 50 μM BRL 49653 (P=0
Trans-p-Coumaric acid
Quassin (hemihydrate) GSK3α/GSK3β at Ser21/Ser9 and Foxo-1/3aQuassin (Nigakilactone D) is a bioactive triterpenoid from stem bark extract of Quassia amara. Quassin inhibits P. falciparum with an IC50 of 0. 15 M. Quassin possesses reversible antifertility, anti estrogenic and anti plasmodial activity. Product information CAS Number: 76 78 8 Molecular Weight: 388. 45 Formula: C22H28O6 Chemical Name: (3aR, 3a1S, 6aR, 7aS, 8S, 11aS, 11bS) 2, 10 dimethoxy 3, 3a1, 8, 11a tetramethyl 3a, 4, 6a, 7, 7a, 8, 11a, 11b