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Functional studies of the first selective beta 3-adrenergic receptor antagonist SR 59230A in rat brown adipocytes
InChiKey: CMYCCJYVZIMDFU-UHFFFAOYSA-N
Probe Reports from the NIH Molecular Libraries Program[Internet]
2016 May 19
Sp-5, 6-dichloro-cBIMPS (sodium salt) Catalog No.:M22522-C Functional studies of the firstKi: 30 nM Sp 5,6 dichloro cBIMPS is a PKA activator. In cell biology, protein kinase A (PKA) is a family of enzymes whose activity is dependent on cellular levels of cyclic AMP. PKA is also known as cAMP dependent protein kinase. PKA has several functions in the cell, such as regulation of sugar, glycogen, and lipid metabolism. In vitro: Sp 5,6 dichloro cBIMPS was found to be both a potent and specific activator of purified cAMP PK and of cAMP PK in
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