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PubMed PMID: 24236947
In vivo UNBS5162 after repeat administration significantly increased survival in orthotopic human prostate cancer models
20S)-10-{[(2S
Pinilla-Ibarz J
Cenerimod Catalog No.:M13534-2 PubMed PMID: 24236947Cenerimod (ACT 334441) is a potent, selective and orally active S1P1 receptor modulator, with an EC50 of 1 nM. Cenerimod shows more than 36fold selctivity for hS1P1 over hS1P2, hS1P3, hS1P4, and hS1P5 receptor subtypes (EC50s=>10000, 228, 2134, and 36 nM, respectively). Cenerimod can attenuate murine experimental autoimmune encephalomyelitis (EAE) and murine sclerodermatous. Product information CAS Number: 1262414 04 9 Molecular Weight: 453. 53