YM-155 - a survivin inhibitor. CAS# 781661-94-7 0263 The MTH1 protein sanitizes oxidized

The MTH1 protein sanitizes oxidized dNTP pools to prevent incorporation of damaged bases during DNA replication

Differential effects between γ-secretase inhibitors and modulators on cognitive function in amyloid precursor protein-transgenic and nontransgenic mice

and growth is inhibited for all cell lines tested

or -20oC for long term (months)

YM-155 - a survivin inhibitor. CAS# 781661-94-7 0263 The MTH1 protein sanitizes oxidizedYM 155, CAS No. 781661 94 7, is a novel survivin suppressant with an IC50 of 0. 54 nM for the inhibition of survivin promoter activity. Sepantronium bromide, also known as YM 155, is a small molecule proapoptotic agent with potential antineoplastic activity. Survivin inhibitor YM155 selectively inhibits survivin expression in tumor cells, resulting in inhibition of survivin antiapoptotic activity (via the extrinsic or intrinsic apoptotic pathways) and