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Chemical Name: N-propyl-3-(pyridin-4-yl)imidazo[1
CAS Number: 566939-85-3
3-dioxoisoindolin-4-yl)amino)heptanoic acid
Molidustat therapy is aldo effective in the treatment of renal anemia in rats with impaired kidney function and
KRN 633 Size:10mg solid Chemical Name: N-propyl-3-(pyridin-4-yl)imidazo[1KRN633 is a potent and selective VEGFR inhibitor. which inhibits tyrosine phosphorylation of VEGFR 2 (IC50 = 1. 16 nmol L) in human umbilical vein endothelial cells. Selectivity profiling with recombinant tyrosine kinases showed that KRN633 is highly selective for VEGFR 1, 2, and 3. KRN633 inhibits tumor growth in several in vivo tumor xenograft models with diverse tissue origins, including lung, colon, and prostate, in athymic mice and rats. KRN633