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Formula: C16H25ClN4O2
9 L/kg and CL of 26 mL/min/kg) and the logPn of 26 is favorable for CNS agent (logPn measured to be 3
and activates pERK in mutant NRAS cell lines
1-1000 nM) elicits Ca2+ influx in mouse and human TRPV4-expressing human embryonic kidney (HEK) cells (EC50 values of 18 and 2
Iptacopan Size:Contact [email protected] for quotation Formula: C16H25ClN4O2Iptacopan (LNP023) is a first in class, orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 value of 10 nM. Iptacopan shows direct, reversible, and high affinity binding to human factor B with a KD of 7. 9 nM. Iptacopan targets the underlying cause of complement 3 glomerulopathy (C3G). Product information CAS Number: 1644670 37 0 Molecular Weight: 422. 52 Formula: C25H30N2O4 Chemical Name: 4 [(2S,4S) 4 ethoxy 1 [(5
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