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Jh-X-119-01 (10 μM) decreases phosphorylation of NF-κB and mRNA levels of IL-6 and TNFα in LPS-treated macrophages in vitro
MMP-2/MMP-9 inhibitor I was found to be able to block MMP-2/MMP-9-dependent invasion in cell culture model
with an EC50 of 105 nM
CAS Number: 20069-09-4
PF-07104091 11388 Jh-X-119-01 (10 μM) decreases phosphorylationPF 07104091 is a potent and selective CDK2 cyclin E1 and GSK3 inhibitor, with Kis of 1. 16 and 537. 81 nM, respectively. PF 07104091 has anti tumor activity for cyclin E1 amplified cancers. (patent WO2020157652A2). Product information CAS Number: 2460249 19 6 Molecular Weight: 404. 46 Formula: C19H28N6O4 Chemical Name: (1R,3S) 3 {3 [3 (methoxymethyl) 1 methyl 1H pyrazole 5 amido] 1H pyrazol 5 yl}cyclopentyl N (propan 2 yl)carbamate Smiles:
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