CAY10603 - HDAC6 Inhibitor. CAS# 1045792-66-2 60169 or in combination with Docetaxel

or in combination with Docetaxel (15 mg/kg) or Irinotecan (25 mg/kg) to significantly reduce the tumor volume

ion channels and 7-TM receptors

but TSC1+/+ cells are resistant

10(7):776-82

CAY10603 - HDAC6 Inhibitor. CAS# 1045792-66-2 60169 or in combination with DocetaxelCAY10603, CAS No. 1045792 66 2, is a potent and selective HDAC6 inhibitor with IC50 of 2 pM. It has 271 nM, 252 nM, 0. 42 nM, 6851 nM, and 90. 7 nM for HDAC1, 2, 3, 8, and 10, respectively. CAY10603 has potent antiproliferative activity against pancreatic cancer cell lines with IC50 of <1 M. It could be useful chemical probe to study HDAC biology. Product information CAS Number: 1045792 66 2 Molecular Weight: 446. 50 Formula: C22H30N4O6 Chemical Name: