Gefitinib - CAS# 184475-35-2 Size:Solid 2 mg LY2109761 was usually used at

LY2109761 was usually used at 5-10 µM in vitro and in cellular assays

1'-biphenyl]-3-carboxylic acid

PubMed PMID: 31602563

CAS Number: 60-56-0

Gefitinib - CAS# 184475-35-2 Size:Solid 2 mg LY2109761 was usually used atGefitinib, also known as ZD1839, is an anilinoquinazoline with antineoplastic activity. Gefitinib inhibits the catalytic activity of numerous tyrosine kinases including the epidermal growth factor receptor (EGFR), which may result in inhibition of tyrosine kinase dependent tumor growth. Specifically, this agent competes with the binding of ATP to the tyrosine kinase domain of EGFR, thereby inhibiting receptor autophosphorylation and resulting in