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77(13 Suppl):Abstract nr 955
InChi: InChI=1S/C17H18BNO5/c1-2-3-8-22-17(20)12-4-7-16(19-10-12)24-14-5-6-15-13(9-14)11-23-18(15)21/h4-7
Expert Rev Anticancer Ther
YL-109 has ability to inhibit breast cancer cell growth and invasiveness in vitro and in vivo
ALX 5407 hydrochloride Size:Contact [email protected] for quotation 77(13 Suppl):Abstract nr 955ALX 5407 is a potent and selective inhibitor of the hGlyT1 glycine transporter. It completely inhibited glycine transport in the GlyT1 cells with an IC50 value of 3 nM . GlyT1 is a family of glycine transporters. Transporters terminate the actions of both glycine and glutamate. There are at least three splice variants in the GlyT1 family, called 1A, 1B, and 1C. GlyT1 is distributed widely throughout the CNS, and that distribution correlates better