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Hideshima T et al
CAS Number: 121714-22-5
9-tetraen-13-yl]-10-hydroxy-5-methoxy-8-methyl-8
Chemical Name: (2R)-2-[6-(4-chlorophenoxy)hexyl]oxirane-2-carboxylic acid sodium
Suramin Size:Contact [email protected] for quotation Hideshima T et alSuramin is a reversible and competitive protein tyrosine phosphatases (PTPases) inhibitor. Suramin is a potent inhibitor of sirtuins: SirT1 (IC50=297 nM), SirT2 (IC50=1. 15 M), and SirT5 (IC50=22 M). Suramin is a competitive inhibitor of reverse transcriptase (DNA topoisomerase II: IC50=5 M). Suramin is a potent SARS CoV 2 RNA dependent RNA polymerase (RdRp) inhibitor. Suramin efficiently inhibits IP5K and is an antiparasitic, anti neoplastic and anti