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CpdA Size:Contact [email protected] for quotation Formula: C17H20Cl2N4O

SKU: 41155643675

4.1
USD100.00 USD122.00

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Description

Formula: C17H20Cl2N4O

InChiKey: ZNSVOHSYDRPBGI-CBQRAPNFSA-N

Smiles: CCNC(=O)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)CCC2C=CC=CC=2)[C@H](O)C[C@@H]1O

Solubility: DMSO : 125 mg/mL (352

CpdA Size:Contact [email protected] for quotation Formula: C17H20Cl2N4OCpdA is a non steroidal selective glucocorticoid receptor modulator. It is an aziridine precursor that can infiltrate cells and is translocated to the nucleus. It inhibits glucocorticoid receptor dimerization, which prevents transcription of gene targets such as NF B and subsequent cytokines through transrepression. Studies have shown contradictory results for binding affinity of CpdA compared with dexamethasone that were either higher (4 fold, IC50 =

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