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SAR-20347 inhibits TYK2- and JAK1-mediated IL-12 and IFN-α signaling
with GI50 less than 100 nM
4 μM in CHO and Xenopus oocyte cells
4-DPCA is found to be effective at inhibiting collagen deposition within and on the outer surface of the disc
PC DBCO-PEG4-NHS ester 22814 SAR-20347 inhibits TYK2- and JAK1-mediatedPC DBCO PEG4 NHS ester is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 2055025 02 8 Molecular Weight: 945. 96 Formula: C47H55N5O16 Chemical Name: 1 {4 [3 ({14 [(3 {2 azatricyclo[10. 4. 0. 0,]hexadeca 1(16),4,6,8,12,14 hexaen 10 yn 2 yl} 3 oxopropyl)carbamoyl] 3,6,9,12 tetraoxatetradecan 1 yl}carbamoyl)propoxy] 5 methoxy 2 nitrophenyl}ethyl 2,5 dioxopyrrolidin 1 yl carbonate Smiles:
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