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2010 May 12
4 nM for CDK4/D1 and CDK6/D1
gastric blood flow is found to be uneven in various regions of the stomach: anterior corpus (50% of total gastric blood flow) greater than posterior corpus (40%) greater than pyloric antrum (7%)
Morizumi S
Gefitinib impurity 2 Catalog No.:M31681-C 2010 May 12Gefitinib impurity 2 is the impurity of Gefitinib. Gefitinib (ZD1839; HY 50895) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity. Product information CAS Number: 246512 44 7 Molecular
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