GO-6976 - CAS# 136194-77-9 10001 Smiles: CC(C)NC[C@H](C1=CC=C(Cl)C=C1)C(=O)N1CCN(CC1)C1=NC=NC2[C@H](O)C[C@@H](C)C=21

Smiles: CC(C)NC[C@H](C1=CC=C(Cl)C=C1)C(=O)N1CCN(CC1)C1=NC=NC2[C@H](O)C[C@@H](C)C=21

protein unfolding

ABT-751 in relapsed childhood acute lymphoblastic leukemia

D'Aniello F

GO-6976 - CAS# 136194-77-9 10001 Smiles: CC(C)NC[C@H](C1=CC=C(Cl)C=C1)C(=O)N1CCN(CC1)C1=NC=NC2[C@H](O)C[C@@H](C)C=21GO 6976, CAS No. 136194 77 9, also known as PD 406976, is a potent inhibitor of neurotrophin receptor intrinsic tyrosine kinase. GO 6976 blocked neurotrophin induced signaling and autophosphorylation of neurotrophin specific tyrosine kinase (Trk) receptors, either Trk B in cortical neurons or Trk A in GT1 1 trk9 cells. Product information CAS Number: 136194 77 9 Molecular Weight: 378. 43 Formula: C24H18N4O Synonym: PD406976 Chemical Name: 3 (13 methyl