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275(28): p
Wnt inhibitor
1) and 5-HT-evoked increases in intracellular calcium (pIC50 = 10
Pilaralisib
Trametinib DMSO solvate - CAS# 1187431-43-1 Catalog No.:M10955-10 275(28): pTrametinib, also known as GSK1120212, is a n orally bioavailable inhibitor of mitogen activated protein kinase kinase (MEK MAPK ERK kinase) with potential antineoplastic activity. Trametinib specifically binds to and inhibits MEK 1 and 2, resulting in an inhibition of growth factor mediated cell signaling and cellular proliferation in various cancers. MEK 1 and 2, dual specificity threonine tyrosine kinases often upregulated in various cancer cell
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