SKI V EG3-OMs 1'-biphenyl]-4-yl]methyl}-2

1'-biphenyl]-4-yl]methyl}-2

[Epub ahead of print] PubMed PMID: 30526042

GGTI-2154 hydrochloride can be used for the research of cancer

a triterpenoid that could be isolated from the Stems of Cucumis melo

SKI V EG3-OMs 1'-biphenyl]-4-yl]methyl}-2SKI V is a noncompetitive and potent non lipid sphingosine kinase (SPHK; SK) inhibitor with an IC50 of 2 M for GST hSK. SKI V potently inhibits PI3K with an IC50 of 6 M for hPI3k. SKI V decreases formation of the mitogenic second messenger sphingosine 1 phosphate (S1P). SKI V induces apoptosis and has antitumor activity. Product information CAS Number: 24418 86 8 Molecular Weight: 254. 24 Formula: C15H10O4 Chemical Name: (2Z) 2 [(3,4