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The variant of UGT1A1 in ~10% of Caucasians which leads to poor metabolization of irinotecan predicts irinotecan toxicity
Formula: C9H11N5O
Chemical Name: 2-[2-(diethylamino)ethyl]-9-hydroxy-5
Ethaselen (5-10 μM
MCH(human, mouse, rat) Catalog No.:M27799-C The variant of UGT1A1 inMCH (human, mouse, rat) is a potent peptide agonist of MCH R and exhibits binding IC50 values of 0. 3nM and 1. 5 nM for MCH1R and MCH2R, respectively. MCH (human, mouse, rat) is a highly sensitive to MCH 2R in a CHO cell line and monitoring mobilization of intracellular calcium with FLIPR, exhibits functional activation EC50 values of 3. 9 nM and 0. 1nM for human MCH 1R and MCH 2R, respectively. Product information CAS Number: 128315 56 0 Molecular